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Psychotria Vidris contains between 0.10%–0.66% alkaloids, most of which is dimethyltryptamine (DMT).
Traditionally, chacruna is also used by some tribes as eyedrops for curing migraine headaches.
Normally, when ingested, DMT is destroyed instantly by the enzyme "Momo-Amine Oxidase" which is in the stomach. However, the harmine and harmaline alkalodis contained in the Banisteriopsis Caapi vine temporarily turn this enzyme off, allowing the Chacruna to work its magic. Caapi itself is one of the best known "Mono-Amine Oxidase Inhibitors" (MAOI).
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